祝贺高志远、贾劭蕊同学“An Activatable Near-Infrared Afterglow Theranostic Prodrug with Self-Sustainable Magnification Effect of Immunogenic Cell Death”文章被Angew. Chem. Int. Ed.接收。-丁丹课题组

祝贺高志远、贾劭蕊同学“An Activatable Near-Infrared Afterglow Theranostic Prodrug with Self-Sustainable Magnification Effect of Immunogenic Cell Death”文章被Angew. Chem. Int. Ed.接收。

2022-08-02

摘要

文章报告了一种治疗诊断前药，它可以通过激活的近红外余辉化学发光自我报告药物释放、免疫原性细胞死亡（ICD）进展和冷热肿瘤转化。这样的智能前药还表现出独特的自持ICD放大效应，通过增强抗肿瘤免疫反应，彻底根除现有肿瘤，防止肿瘤进一步复发。

Angewandte Chemie International Edition. (IF 16.823) DOI: 10.1002/anie.202209793